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Description

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31 patients with depressive disorder (DD) and 29 patients with mixed anxiety and depressive disorder (MADD) were registered at the Department of Paediatric Psychiatry of the Faculty of Medicine of Comenius University and The National Institute of Childrens Diseases in Bratislava and met the inclusion criteria (age 8-18 years, diagnosis of DD or MADD)

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The GHRH pathway, mediated by the GHRH receptor (a class II G-protein coupled receptor), primarily couples to Gs proteins, activating adenylyl cyclase to increase intracellular cAMP levels

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