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The UPR, crucial for innate and adaptive immunity, is activated in this situation, suggesting its role in regulating and maintaining the immune response in vitiligo.42 Another recent study analyzed the role of mitochondrial energy metabolism in melanocytes from vitiligo patients, finding reduced ATP production, increased proton leakage, altered expression of glycolytic enzymes, and hyperactivity of the PGC1 axis
doi: 10.1124/jpet.107.120311 120 MedhurstA
The joint action of unfolded protein response, circZc3h4, and circRNA scar in procymidone-induced testicular injury in adolescent mice
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Thiacloprid impairs reproductive functions of male Wistar rats
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