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Endogenous Nrf2 is activated after ischemic stroke, resulting in an initial increase in the expression of overall Nrf2 protein and a subsequent decrease in the ischemic zone (Tian et al., 2020
Studies by Schaefer and colleagues suggest that exposure of P7 mice to 1.5% isoflurane for 4 h or PSD-95 PDZ2WT peptide decreases the efficiency of neuronal NO synthase (nNOS) by inhibiting proteinprotein interaction between PSD-95 PDZ, NMDA NR2, and nNOS
This supports that the short-term anti-diabetic effect of GLP-1 is mainly due to slowing of gastric emptying and consequently a reduced rate of carbohydrate absorption
This preemptive antiviral state limits initial viral replication, thereby attenuating early disease progression (493)
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