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Its cardioprotective properties also will provide significant benefits for those with AFS
For example, Nordisks $1.08 billion acquisition of Emisphere Technologies to secure oral delivery capabilities, and co-development agreements like the one between Pfizer and OPKO Health for oral GLP-1s, are accelerating innovation cycles and expanding access
Reported EC values in transfected cell assays sit in the sub-nanomolar to low-nanomolar range at MC1R and MC4R, with roughly an order of magnitude lower potency at MC3R and MC5R, and it is essentially inactive at MC2R, the adrenocorticotropin receptor
How PlexusDx Supports a More Personalized Approach PlexusDx's Precision Peptide Genetic Test may help provide context by revealing predispositions in key GLP-1 pathway genesincluding GIPR rs1800437, FTO rs9939609, and MC4R rs17782313
Wang H et al
