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In male rats experiencing transient ischemic stroke, UA treatment induced IL-6 expression, upregulated STAT3 and NF-B p65 phosphorylation, induced Socs3 expression, and maintained the ramified morphology of Iba-1-positive microglia in the cerebral cortex, suggesting an anti-inflammatory effect of UA [54]

In Depression, Firmicutes (primarily the genera Clostridium, Enterococcus, Lactobacillus , and Faecalibacterium ) and Bacteroidetes (particularly the species Bacteroides and Prevotella ) account for over 90% of the adult gut microbiota (61)

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Analytical Cell Pathol (2021) 2021