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EDS diagnosis is often missed because symptoms vary widely and may be invisible. A Comprehensive EDS Evaluation May Include: Detailed family history and genetic risk assessment Heart and blood vessel imaging Testing for autonomic dysfunction (e.g., POTS) Mast cell and histamine sensitivity evaluation Postural and movement assessments Doctors also consider overlooked symptoms such as: Chronic fatigue Brain fog Bloating Heat intolerance Related Reading: Ehlers-Danlos Syndrome (EDS) : Hypermobility Diagnosis, HSD vs hEDS & Treatment Approach Cardiac autonomic testing and treating heart disease