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Mechanistically, total intracellular iron alone is not the whole storyhow a tumor uses iron (for DNA repair, energy metabolism, redox buffering, etc.) and the cells lineage-specific biology determine whether ferritin acts mainly as a protective iron reservoir or as a regulator of metabolism and redox state [3, 88]

Discovering and developing new peptides is a rapidly developing area of science, particularly peptides derived from the mysterious part of the human genome referred to as junk DNA

Glial cells (astrocytes and microglia) play important roles in maintaining CNS homeostasis through some processes, including reduction of oxidative stress

Cysteine degradation and energy metabolism Although the role of cysteine degradation in cancer development has predominantly been explored regarding H 2 S production, the usefulness of cysteine as a carbon source is also evident along its catabolic pathways, as its degradation gives rise to other organic compounds relevant for carbon and energy metabolism (Fig