That tradeoff only makes sense when a clinician sees a clear reason in your case
as to mitochondrial GSTs and MAPEG, we refer the reader to other excellent reviews 7,8
J Cell Biol 194(1):715 Friedmann Angeli JP, Schneider M, Proneth B, Tyurina YY, Tyurin VA, Hammond VJ, Herbach N, Aichler M, Walch A, Eggenhofer E, Basavarajappa D, Rdmark O, Kobayashi S, Seibt T, Beck H, Neff F, Esposito I, Wanke R, Frster H, Yefremova O, Heinrichmeyer M, Bornkamm GW, Geissler EK, Thomas SB, Stockwell BR, ODonnell VB, Kagan VE, Schick JA, Conrad M (2014) Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice
This may improve mood, clarity, and cognitive function
NAD+ levels naturally decline with age