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Comparisons With Other Diabetes Therapies Putting GLP1s in context with other antidiabetic agents offers additional insights: Thiazolidinediones (TZDs) are associated with increased fracture risk, especially in women SGLT2 inhibitors have raised concerns in some trials, particularly canagliflozin DPP-4 inhibitors appear largely neutral regarding skeletal effects Against this backdrop, GLP1s may have a neutral or possibly safer profile, though the data are not conclusive

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We used the small sample adjustment to the Score test, J/(J-1) where J is the number of clusters [37] When both random and fixed effects were analyzed, a mixed effect longitudinal analysis was performed

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(1) Believe it or not, vitamin B12 is often over-supplemented by athletes taking multivitaminsand reaching for energy drinks or a B12 energy shot during the day