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BPC-157 is not approved by Health Canada or the FDA for human use
Trias I et al
A large preclinical toxicity program run across mice, rats, rabbits, and dogs found BPC-157 well tolerated with no serious treatment-related toxicity, no identifiable lethal dose, and no genotoxic or teratogenic signal, which is the strongest safety data point available by Xu 2020
While these specific proteins were not significantly elevated in the sibling validation cohort, computational predictions based on (s)PLS-DA analysis did identify proteins associated with immunity and inflammatory responses such as Zinc-alpha-2-glycoprotein (AZGP1) and Carboxypeptidase B2 (CPB2) as being important contributors to group separation 48,49,50
The compound inhibits the NNMT enzyme in fat cells, which increases cellular NAD+ levels and shifts adipocyte metabolism from fat storage to fat burning
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