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Vegans and Vegetarians: B12 is found almost exclusively in animal products, so those on plant-based diets must use fortified foods or supplements Older Adults: reduced stomach acid can decrease B12 absorption from food as we age People with Pernicious Anemia: this autoimmune condition prevents the body from making intrinsic factor, a protein needed for B12 absorption Individuals with Gastrointestinal Conditions: diseases like Crohn's or Celiac disease can impair nutrient absorption Patients Who Have Had Gastric Surgery: procedures like gastric bypass can reduce the body's ability to absorb B12 Certain Medications: drugs such as Metformin and proton pump inhibitors (PPIs) can interfere with B12 absorption It's important to distinguish between using vitamin b12 injectable for humans for a diagnosed medical need versus for general wellness

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PLoS One 10 (4), e0123454

Scientists have turned a number of peptides into safe and effective drugs, including insulin, which moves sugar from blood into cells, and GLP-1 (the P stands for peptide), which helps regulate appetite and is used in weight-loss medications such as Ozempic

A dose that is effective in a rat cannot be directly scaled to humans by body weight