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42 PULMONARY DISEASE GSH deficiency has been proposed to have a role in the pathophysiology of a number of lung diseases, including chronic obstructive pulmonary disease, 46 acute respiratory distress syndrome (ARDS), 47-49 neonatal lung damage, 50 and asthma

10.1093/nar/gkab951 Summary Keywords glutathione synthetase deficiency, 5-oxoprolinuria, glutathione synthetase gene variation, newborn, inherited metabolic disease, case report Citation Wu X, Jiao J, Xia Y, Yan X, Liu Z, Cao Y and Ma L (2023) Case report: A Chinese patient with glutathione synthetase deficiency and a novel glutathione synthase mutation

A critical initiating event in neuroinflammation is the detection of homeostatic disturbances within the CNS

NDA filing expected Q4 2026

This method can be effective, particularly for individuals with respiratory conditions or those requiring rapid increases in glutathione levels