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Neuroprotection research includes hippocampal ischemia-reperfusion models in rats (PMID 32558293) and investigations into the brain-gut axis as a candidate explanatory framework for the broad effects observed across tissue types (PMID 27138887)

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Its broad receptor engagement profile has made it a frequently used tool compound in studies of melanocortin receptor pharmacology, particularly in investigations of MC4R-mediated pathways related to energy homeostasis and MC3R involvement in inflammation research models

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