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Where PDA modulates nitric oxide, TB-500 reduces inflammatory cytokines through separate pathways

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GHK-Cu is one of the most extensively characterized signaling peptides in human biology, modulating over 4,000 genes including upregulation of tissue repair, collagen synthesis, and antioxidant defense pathways, while downregulating inflammatory and cellular senescence-associated genes

Radiotherapy inhibits tumor growth by generally inducing tumor cell apoptosis, necrosis, mitotic catastrophe, autophagy, or senescence through inflicting extensive DNA damage, including DNA-protein crosslinking, or transiently increasing the levels of cytotoxic reactive oxygen species (ROS) (Baskar et al., 2012