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TD: Tardive Dyskinesia for total (+) active metabolites for tetrabenazine & deutetrabenazine Schneider et al (2021) Adapted from Diana (2007), Schneider et al (2021) & Cheung & Parmar (2022) References: Aminoff MJ (2024): Pharmacologic Management of Parkinsonism & Other Movement Disorders (Chapter 28)

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1 2 3 4 5 Clinical oral medicine and pathology

Many of the cardiovascular and metabolic trials informing the discussion were not designed to evaluate ophthalmic outcomes. The authors called for prospective ophthalmology-specific studies incorporating imaging biomarkers, visual outcomes and disease-specific monitoring, noting that parsing the protective benefits or adverse effects of this rapidly growing medication class will be essential to refining disease management and improve patient outcomes. As GLP-1 therapies become increasingly common among patients with diabetes, obesity and vascular comorbiditiesprecisely the populations populating ophthalmic clinicsthe field may not have the luxury of waiting for cleaner data

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