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Decisions about continuing or stopping treatment should be made with a healthcare provider, considering: Weight loss progress Side effects experienced Personal health goals Other medical conditions Alternatives and Complementary Strategies While GLP-1 agonists can be powerful tools, they are not the only option for weight loss
Indeed, RYGB, which causes marked gastrointestinal distension due to how it forces food passage through the reconfigured gastrointestinal tract, leads to the same central pattern of neuronal activation as activating GLP-1R-expressing and OXR-expressing vagal afferents in mice [31, 36, 37], while vagotomy partially prevents the appetite suppression and weight loss caused by RYGB in rats [38]
Ongoing research is needed to find out why some people benefit more than others and how to optimize results for all
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