Anyone outside a healthy, monitored research context and especially anyone in one of the sensitive groups above sits entirely beyond the edge of what has been studied, which is exactly why a clinicians judgement, not a web page, is the right place for that decision to be made
How it relates to adjacent compounds The nearest catalogue neighbour by subject matter rather than chemistry is NAD, since NNMT activity sits upstream of nicotinamide availability and therefore of the salvage route that supplies the dinucleotide
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consideration will then be given to the changes in this overall picture brought about by the educational experiment