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RBPs have been implicated as important regulators in various physiologic and pathologic conditions by regulating gene expression post-transcriptionally, including RNA splicing, modification, localization, stability, and protein translation ( Breast cancer ranks as the most prevalent cancer among women globally, with over 70% of patients falling into the estrogen receptor-positive (ER+) category ( 2 Materials and methods 2.1 Cell lines and reagents MCF-7, T47D, BT474, MDA-MB-231, and HEK-293 T cell lines used in this study were purchased from the American Type Culture Collection (ATCC)

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