For example, in a 2021 study, as little as 100mg of dihydroberberine increased berberine blood levels better than 500mg of HCl, and another 2021 study (by Indena, the company that makes Berbevis) found that a phytosomal preparation resulted in a tenfold improvement in bioavailability compared with HCl.48 51 Based on these studies, you might conclude that the two bioenhanced forms are superior to berberine HCl
Furthermore, studies have confirmed the presence of physiologically relevant concentrations of BAs species in ovarian tissue, along with expression of FXR and BAs transporters (68)
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But most of these drugs are not approved for human consumption by regulators, because we dont fully understand what theyre doing to our bodies
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