With increasing frequency over the past few years, optometrists across the country have gotten referrals from internists requesting baseline diabetic retinopathy (DR) screenings for patients about to start therapy with one of the glucagon-like peptide-1 (GLP-1)/glucose-dependent insulinotropic polypeptide (GIP) receptor agonists such as semaglutide (Ozempic, Novo Nordisk), tirzepatide (Mounjaro, Eli Lilly) and dulaglutide (Trulicity, Eli Lilly
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Recently, it has gained prominence for its potential benefits in promoting weight loss and improving overall well-being
The body essentially decides that maintaining existing hair follicles is less important than preserving organ function and basic metabolic processes
Rabbit anti-GLP-1R antibody, mouse anti-glial fibrillary acidic protein (GFAP) and mouse anti-alpha smooth muscle actin ( -SMA) were from Abcam PLC (Cambridge, UK), Goat anti-type I collagen antibody from Southern Biotechnology (Birmingham, AL, USA), rabbit antibody against glyceraldehydes-3-phosphate dehydrogenase (GAPDH) from Trevigen (Gaithersburg, MD, USA) and anti-rabbit IgG Alexa488-conjugated antibody, anti-mouse-IgG-Alexa555-conjugated antibody, anti-goat-IgG-Alexa350-conjugated antibody and Hoechst33342 were from Invitrogen (Carlsbad, CA, USA)