why isn't my tirzepatide working 7 Reasons You Aren't Losing Weight on Weight Loss Drugs Expert GLP-1 Tirzepatide Weight Loss

It is not the same as Ozempic or Wegovy, is not FDA-approved, and has not been evaluated by the FDA for safety or efficacy

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The half-life (t 1/2 ) of tirzepatide is 5.4 days in humans (Schneck and Urva 2024), which is comparable to that of semaglutide in humans (t 1/2 = 168 h) (Jensen et al