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Signals to decrease your maintenance dose: You are still losing weight unintentionally after 8 weeks at goal You experience persistent nausea, constipation, or diarrhea that interferes with daily life Your BMI drops below the healthy range (under 18.5) You have maintained goal weight for 6 or more months and want to test a lower dose Signals to increase your maintenance dose: Weight has increased by 5 or more pounds over 4 consecutive weeks Appetite and cravings have returned to pre-treatment levels You have experienced a major life stressor (job change, illness, injury) that disrupts diet and exercise routines Seasonal weight gain exceeds your historical pattern by 3 or more pounds How to adjust: Move in 2.5 mg increments

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