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Moreover, the benefits were seen as early as 3 months after starting supplementation and grew with time
However, an in vitro study published in *Nutrients* in 2021 suggests that, at doses that are suboptimal when taken individually, the combination of creatine monohydrate and L-carnitine tartrate triggers an anabolic responsespecifically in terms of muscle protein synthesisthat neither compound can produce on its own
Common practice splits the daily amount into once or twice daily doses
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