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277 Beyond these metabolic effects, GLP-1 RAs exert broad anti-inflammatory actions and modulate pathways implicated in biological aging, including improving lipid metabolism, restoring endothelial function, activating AMPK, and inhibiting mTOR
EXSCEL and REWIND had a larger percentage of patients without established CVD, (EXSCEL 30%, REWIND 68.5%) lending evidence for extrapolation of use of this class of agents to the primary prevention of CVD in T2DM
Health 114, 109110
W., Maddukuri, S., Karanfilian, K
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