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Patients were allowed to increase the insulin dose only up to the starting insulin dose prior to randomization
Once carnitine metabolism is disrupted, it is not only a reflection of impaired renal function, but also may promote the occurrence and progression of DKD through mitochondrial energy dysfunction, oxidative stress and inflammatory responses
doi: 10.1210/er.2013-1071 78 FrystykJIvarsenPSkjaerbaekCFlyvbjergAPedersenEBOrskovH
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