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On average, research shows a 5% reduction in starting body weight after 12 weeks, with continued weight loss over six months to a year

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Eli Lilly's TRIUMPH Phase 3 program includes multiple trials across different populations: TRIUMPH-1: Obesity without type 2 diabetes (NCT05929066) TRIUMPH-4: Obesity with type 2 diabetes Additional trials: MASLD/NASH, cardiovascular outcomes, kidney outcomes What Trial Enrollment Includes Free study medication (retatrutide or placebo

Clinical data show that these symptoms are often temporary and tend to occur during dose escalation