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No published Phase I trial establishing tolerability, human pharmacokinetics or dose escalation was identified

Over-the-counter products contain 1-2% glutathione and may include ingredients that boost glutathiones antioxidant activity, such as ascorbic acid, ferulic acid, and tocopherol

Oxygen radicals insert into the C-H bonds of PUFAs, generating lipid hydroperoxides and elevating levels of ROS, which induce ferroptosis (55)

Dendrobium officinale polysaccharide (DOP) attenuates liver fibrosis by preserving intestinal barrier integrity and upregulating tight junction proteins