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Understanding this mechanism matters because it explains why most GI side effects are dose-dependent, temporary, and manageable through titration strategies

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It was first described in the scientific literature in 1993 and has since accumulated a substantial body of preclinical research across soft tissue, gastrointestinal and musculoskeletal contexts

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Results showed that BPC-157 apparently reduced the cell number in the G0/G1 phase in a dose-dependent manner compared with the number in the control group (Figure 4B)

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