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In addition, this uncontrolled immune response could be potentiated by impaired pituitary function due to autoimmune damage, which manifests in symptoms varying in severity, such as fatigue, orthostatic hypotension and sleep disturbances, depending on the degree of pituitary damage (42, 59)

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Unless and until large, well-designed human trials clarify safety and efficacy, BPC-157 remains an unapproved peptide, subject to regulatory controls and compliance requirements in drug-tested populations

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