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However, during the initial weeks particularly around dose increases mild fatigue is not uncommon and may be related to reduced caloric intake or the body adapting to altered metabolism

Moreover, stress can compromise the skins natural barrier function, making it more susceptible to environmental damage and dehydration

Effects of dapagliflozin on major adverse kidney and cardiovascular events in patients with diabetic and non-diabetic chronic kidney disease: a prespecified analysis from the DAPA-CKD trial

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