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(Czechia) Validated assay content 10.71 mg Purity greater than 99.8 percent Retention time and spectral identity confirmation Endotoxin level 0.0120 EU per mg No detectable microbial contamination No detectable heavy metals For research use only not for human or veterinary use For laboratory research only

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Sociodemographic characteristics Diagnosis (vitamin B12 deficiency or pernicious anaemia), age, sex, education level, employment status, country of residence (England, Wales, Scotland, Northern Ireland, Republic of Ireland), region of residence (nine English regions, according to the Office for National Statistics, Wales, Scotland, and Northern Ireland) were assessed using the questions in Supplementary Table S1

Alternative GLP-1 receptor agonists If semaglutide causes significant side effects or concerns about b12 status arise, other GLP-1 medications offer alternatives