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Arancio O et al
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(2) Plasma-membrane lipid bilayer: ROS attacks membrane PUFAs, driving lipid peroxidation and generating cytotoxic aldehydes such as malondialdehyde (MDA) and 4-hydroxynonenal (4-HNE), which compromise membrane integrity and fluidity and impair motility/fertilization-related functions
doi: 10.3390/biom9110649
Timeline: Liver enzyme improvements (AST/ALT normalization) documented at 4-8 weeks in clinical studies
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