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Storage temperature, time since mixing, and handling all affect how much active peptide remains in the later doses from a vial
There is still a negative deflection for 9/12mg arms suggesting we have not reached max reduction in A1c and keep in mind this is retatrutide alone, with no other medications allowed
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Some patients feel changes within 12 hours
thus, it can circumvent the degradation of dipeptidyl peptidase-4 (DPP-4) and has a prolonged intravenous half-life of 30 min and a 23 h half-life after subcutaneous administration
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