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The reasons people do not lose weight on semaglutide are usually different from the reasons phentermine fails, which is why cross-class switching can produce different outcomes
However, prolonged exposure to GLP-1RAs can lead to tachyphylaxis, reducing their effect on gastric emptying over time
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The top row (AD) shows the GSH-edited spectra and the bottom row (EH) shows the GABA+-edited spectra
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