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8,9,30 The agents used in these trials, including higher-dose semaglutide (2.4 mg) and the dual GLP-1/GIP receptor agonist tirzepatide, have demonstrated compelling benefits
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In clinical trials, patients using semaglutide 2.4 mg weekly achieved average weight loss of 1215% of body weight over 68 weeks (approximately 26-33 lbs for a 220-lb person), substantially greater than placebo
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