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A B12 deficiency in females can cause symptoms such as fatigue, tingling feet, or depression
Oral supplementation (50150 g daily) may suit dietary deficiency without nerve involvement, but malabsorption cases require injections
Intramuscular placement goes deeper when large muscle groups or thick connective structures sit at the center of the plan
Long-term studies show sustained safety, though most research covers acute to subacute periods (weeks to months)
The reality check: longer trials did not justify a commercial obesity drug The same obesity-pharmacotherapy review literature notes that development was terminated after a longer trial failed to demonstrate sufficiently meaningful weight loss to be commercially viable
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