Not that this has not been demonstrated before but to my surprise the questions on thyroid tumors and GLP-1 RA keep coming especially from non-endocrinologists This was a huge study that included a total of 460,032 users of GLP-1RAs, 717,792 users of SGLT2is, 2,055,583 users of DPP-4is, and 1,119,868 users of SUs GLP-1RA exposure was not associated with an increased risk of thyroid tumors compared with SGLT2is, DPP-4is, or SUs (meta-analysis: GLP-1RA vs
For photoprotection studies, UV-irradiated controls without MT-1 pre-treatment establish baseline DNA damage levels for comparison
Abbreviations ARC: Arcuate nucleus CNO: Clozapine-N-oxide EA: Electroacupuncture GLP-1: Glucagon-like peptide-1 GLP-1R: GLP-1 receptor GVND: Gastric vagal deafferentation NTS: Nucleus tractus solitarius taVNS: Transcutaneous auricular vagus nerve stimulation POMC: Pro-opiomelanocortin NPY: Neuropeptide Y Vmax: Maximum voltage Vrms: Effective voltage ANOVA: Analysis of variance References Collaborators GBDO, Afshin A, Forouzanfar MH, Reitsma MB, Sur P, Estep K, et al
Acknowledgements Guizhou Provincial Science and Technology Plan Project [Qiankehe Fundamentals ZK (2023) General 392]
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