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Therefore, these results indicate that the inhibition of NF-B pathway contributes to promote SGNs survived from peroxynitrite injury, and that GPX1 protects SGNs against peroxynitrite-induced damage, at least in part, via blocking the NF-B pathway activation

The analysis led to generally consistent results, which were similar to the primary analysis between cohorts of new users of GLP-1RAs compared with new users of SGLT2 inhibitors, metformin or other second- or third-line medications

Wolpin BM, Bao Y, Qian ZR, Wu C, Kraft P, Ogino S,

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Planned follow-up visits required to assess adherence and clinical response