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Hypoglycaemia risk increases when GLP-1 agonists are combined with insulin or sulphonylureas, requiring careful medication review and dose adjustment
When macrophages are recruited by adipose tissue due to the overexpression of monocyte chemoattractant protein 1 (MCP1, a chemokine ligand also known as CCL2), hepatic insulin resistance is observed with increased TNF expression in adipose tissue, but without any change in body weight or adiposity [148]
According to Engel, he started taking Ozempic in 2023, after his doctor prescribed the drug to help him manage his diabetes
Stick to patients where theres a clear psychiatric connection (medication side effects, binge eating disorder, depression complicating weight loss), establish physician collaboration for protocols, and document your competence through training or additional certification
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