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Chronic dietary l-carnitine supplementation in mice altered cecal microbial composition, markedly enhanced synthesis of TMA and TMAO, and increased atherosclerosis, but this did not occur if intestinal microbiota was concurrently suppressed

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doi:10.1136/practneurol-2014-001071

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It is currently in phase III clinical trials under the REDEFINE program

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Cagrilintide is studied in preclinical research on amylin and calcitonin receptor signaling, food intake regulation, body composition partitioning, and combination research with incretin pathway molecules

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