In the cerebral cortex, GLP-1R is expressed on neurons and glia [42], while in the spinal cord, GLP-1R is coexpressed only with microglia [20]
Together, these mechanisms are associated with enhanced regenerative capacity and attenuation of inflammatory responses, particularly within gastrointestinal tissue models (5) Preclinical investigations have explored the influence of BPC-157 on nervous system recovery following traumatic injury
But the time to see research results varies
Brain 146(5):18211830 Rubino DM et al (2022) Effect of Weekly Subcutaneous Semaglutide vs Daily Liraglutide on Body Weight in Adults With Overweight or Obesity Without Diabetes: The STEP 8 Randomized Clinical Trial
Investigating cardiovascular health outcomes is critical, as weight loss may reduce long-term risks of hypertension, atherosclerosis, and insulin resistance