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The SURMOUNT-1 trial that established tirzepatide for chronic weight management capped doses at 5, 10, and 15 mg and produced 20.9% mean body-weight reduction at 15 mg over 72 weeks (Jastreboff et al., 2022)

The absence of a gallbladder does not fundamentally prevent these medications from working or create an automatic safety concern

(2007): Metabolic effects of a growth hormone-releasing factor in patients with HIV

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Women who attribute decreased desire entirely to semaglutide may be overlooking concurrent stressors that would suppress libido regardless of medication