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Michael Calore: All right, let's take a quick break and we'll come right back
The FDA-approved prescribing information for both Mounjaro and Zepbound does not mandate a specific weaning protocol, and there is no evidence of a physiological withdrawal syndrome associated with abrupt cessation
Results: Mounjaro: 20.2% average weight loss Wegovy: 13.7% average weight loss Waist circumference reduction: 18.4cm (Mounjaro) vs 13.0cm (Wegovy) Achieving 20%+ weight loss: 1 in 3 Mounjaro patients vs significantly fewer on Wegovy Thats about 47% more weight loss on average with Mounjaro
Semaglutide is a GLP1 receptor agonist, originally developed for type 2 diabetes management
Competing interest The authors declare that they have no competing interests
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