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GLP-1s not found to increase risk of ischemic optic neuropathy Several observational studies have suggested that GLP-1 treatment in people with diabetes may increase the risk of non-arteritic anterior ischemic optic neuropathy (NAION), a condition that can cause blindness

Results are self-reported

For Canadian researchers, the practical takeaways: All three engage GHRH receptors as primary mechanism Sermorelin = GHRH(1-29) native sequence CJC-1295 = modified GHRH(1-29), with or without DAC for albumin binding Tesamorelin = full GHRH(1-44) with N-terminal trans-3-hexenoic acid stabilization Half-life range: minutes (sermorelin, CJC-1295 no DAC, tesamorelin) to days (CJC-1295 with DAC) For continued reading, see What Is Tesamorelin

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NNMT as a regulator of metabolic health and adiposity