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[9] Visual disturbances have been reported in patients with Leber hereditary optic neuropathy, and rapid B12 administration may precipitate optic nerve atrophy in this genetically predisposed population, mandating extreme caution or alternative therapy
Dolan ME, Mitchell RB, Mummert C, Moschel RC, Pegg AE
Ischemic cells compensate for reduced oxygen delivery by increasing anaerobic glycolysis, leading to acidosis as well as glucose derivatives that promote signaling related to oxidative stress and inflammation [38, 57, 62]
In contrast, there is limited research regarding glutathione supplementation during pregnancy
Glutathione may have a limited impact in patients already using medications with anti-inflammatory mechanisms, such as ketamine in treatment-resistant depression
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