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doi:10.1016/0304-4165(75)90205-6 Huang CS, Moore WR, Meister A
The cyclization step, involving the -amino group of lysine and -carboxy group of aspartic acid, was performed using an 8-fold excess of DCC as the coupling agent and 1-hydroxybenzotriazole (HOBt) as a racemization suppressant
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