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Retatrutide pharmacokinetics on the plotter With a half-life of approximately six days, retatrutide sits between semaglutide (seven days) and tirzepatide (five days) in terms of weekly persistence
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![Tirzepatide vs. Semaglutide: Which GLP-1 Better Preserves Muscle? [SURMOUNT-5 Data]](https://www.clinicalnutritioncenter.com/wp-content/uploads/2026/04/research-image-2026-04-10-1024x559.jpg)