Requirements of vitamin B12 in excess of normal (due to pregnancy, thyrotoxicosis, hemolytic anemia, hemorrhage, malignancy, hepatic and renal disease) can usually be met with oral supplementation
However, the limited human clinical trial data means that the long-term safety profile in humans is not fully characterized
Advances in screening, early diagnosis and accurate staging of diabetic neuropathy
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Paresthesia in hands and feet Many adults and children who have experienced a vitamin B12 deficiency have experienced paresthesia, which refers to a burning or pins-and-needles sensation in certain areas of the body, like the hands and feet