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More serous B12 deficiencies have the potential to impair heart and neurological function, leading to a wide range of serous symptoms, including but not limited to tinnitus, severe joint pain, memory problems, depression, anxiety, poor muscle function, ataxia, and changes in reflexes

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By contrast, the k cat values of the ketosteroid isomerase activity of human, equine, and marmoset GST A3-3 are two orders of magnitude higher, ranging between 204 and 261 s 1 (Ismail et al., 2021)

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