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Doxycycline is notorious for esophageal irritation if taken with insufficient water or while lying down, while tirzepatide commonly causes mild to moderate nausea during dose escalation
Zhai et al., 2025)
Nat Rev Endocrinol (2019) 15(5):28898
The findings were reported in the paper Bimagrumab and semaglutide alone or in combination for the treatment of obesity: a phase 2 randomized clinical trial, published in the journal Nature Medicine (Springer Nature)
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